ColReorder provides the ability to specify a column ordering which is not that of the HTML (which typically you will want) through the parameter oColReorder.aiOrder. This is an array of integers with the column ordering you want.
$(document).ready( function () { var oTable = $('#example').dataTable( { "sDom": 'Rlfrtip', "oColReorder": { "aiOrder": [ 4, 3, 2, 1, 0 ] } } ); } );